Every year, four exhibitions are curated in Light Work’s Kathleen O. Ellis Gallery, each accompanied by an issue of Contact Sheet. Other exhibition venues include Light Work’s Hallway Gallery, the Community Darkrooms Gallery, and the Robert B. Menschel Photography Gallery. Light Work regularly collaborates with the Urban Video Project (UVP), the Everson Museum of Art, and other organizations and galleries in Syracuse. Satellite exhibitions are occasionally held at the Palitz Gallery at the Syracuse University Lubin House in New York City.

Light Work has presented over 400 exhibitions since 1973.